AMITRIPTYLINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does amitriptyline mean? 

• AMITRIPTYLINE (noun)
  The noun AMITRIPTYLINE has 1 sense:

1. a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications

  Familiarity information: AMITRIPTYLINE used as a noun is very rare.

 Dictionary entry details 

• AMITRIPTYLINE (noun)

Sense 1

Meaning:

A tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications

Classified under:

Nouns denoting man-made objects

Synonyms:

amitriptyline; amitriptyline hydrochloride; Elavil

Hypernyms ("amitriptyline" is a kind of...):

tricyclic; tricyclic antidepressant; tricyclic antidepressant drug (an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain)

 Context examples 

Amitriptyline likely produces antineuralgic effects via modulation of multiple subtypes of glutamate (Glu) receptors, independent of its antidepressant actions.

(Baclofen/amitriptyline/ketamine gel, NCI Thesaurus)

Also called baclofen/amitriptyline/ketamine gel.

(BAK gel, NCI Dictionary)

A centrally acting muscle relaxant, chemically similar to amitriptyline hydrochloride with antidepressant activity.

(Cyclobenzaprine Hydrochloride, NCI Thesaurus)

A topical preparation containing the antidepressant amitriptyline and the excitatory amino acid antagonist ketamine with potential topical analgesic activity.

(Ketamine/Amitriptyline NP-H Cream, NCI Thesaurus)

Amitriptyline is a type of tricyclic antidepressant.

(Amitriptyline, NCI Dictionary)

It contains three drugs, baclofen, amitriptyline, and ketamine, that relax muscles by blocking nerve receptors.

(Baclofen/amitriptyline/ketamine gel, NCI Dictionary)

Amitriptyline inhibits the re-uptake of norepinephrine and serotonin by the presynaptic neuronal membrane in the central nervous system (CNS), thereby increasing the synaptic concentration of norepinephrine and serotonin.

(Amitriptyline, NCI Thesaurus)

The hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive activities.

(Amitriptyline hydrochloride, NCI Thesaurus)

Amitriptyline hydrochloride is a type of tricyclic antidepressant.

(Amitriptyline hydrochloride, NCI Dictionary)

A topical preparation of baclofen, amitriptyline, and ketamine compounded in a penetration-enhancing polaxamer-lecithin organogel (PLO) with potential antineuralgic activity.

(Baclofen/amitriptyline/ketamine gel, NCI Thesaurus)