ALLOGENEIC

Pronunciation (US):

(GB):

 Dictionary entry overview: What does allogeneic mean? 

• ALLOGENEIC (adjective)
  The adjective ALLOGENEIC has 1 sense:

1. denoting or relating to cells or tissues from individuals belonging to the same species but genetically dissimilar (and hence immunologically incompatible)

  Familiarity information: ALLOGENEIC used as an adjective is very rare.

 Dictionary entry details 

• ALLOGENEIC (adjective)

Sense 1

Meaning:

Denoting or relating to cells or tissues from individuals belonging to the same species but genetically dissimilar (and hence immunologically incompatible)

Antonym:

xenogeneic (denoting or relating to cells or tissues from individuals belonging to different species)

Derivation:

immunology (the branch of medical science that studies the body's immune system)

 Context examples 

Upon intratumoral administration of the allogeneic dendritic cell vaccine COMBIG-DC, these activated DCs attract natural killer (NK) cells, induce an anti-inflammatory response leading to the induction of NK-cell-mediated tumor cell death.

(Allogeneic Dendritic Cell Vaccine COMBIG-DC, NCI Thesaurus)

A cell-based vaccine composed of allogeneic dendritic cells pulsed ex-vivo with an autologous myeloma idiotype with potential antineoplastic activity.

(Allogeneic Dendritic Cell-Myeloma Idiotype Vaccine, NCI Thesaurus)

A population of allogeneic cytotoxic T lymphocytes (CTLs) specifically reactive to the herpes virus cytomegalovirus (CMV) with potential immunomodulating and antiviral activities.

(Allogeneic Cytomegalovirus-Specific Cytotoxic T lymphocytes, NCI Thesaurus)

Upon infusion of allogeneic CD56-positive CD3-negative natural killer (NK) cells, these cells are able to secrete cytokines and recognize and kill tumor cells as well as virally-infected cells.

(Allogeneic CD56-positive CD3-negative Natural Killer Cells, NCI Thesaurus)

A syndrome of immologically mediated tissue damage occurring following allogeneic transplant usually affecting the skin, liver, and gi tract.

(Acute Graft Versus Host Disease, NCI Thesaurus)

A preparation of allogeneic Epstein-Barr virus (EBV) specific cytotoxic T-lymphocytes (CTL) with potential antineoplastic activity.

(Allogeneic Epstein-Barr Virus-Specific Cytotoxic T-Lymphocytes, NCI Thesaurus)

Transplantation may be autologous (the patient's own blood cells are used), allogeneic (blood cells are donated by someone else), or syngeneic (blood cells are donated by an identical twin).

(Peripheral Blood Stem Cell Transplantation, NCI Thesaurus)

Transplantation may be autologous (an individual's own blood cells saved earlier), allogeneic (blood cells donated by someone else), or syngeneic (blood cells donated by an identical twin).

(Peripheral Blood Stem Cell Transplantation, NCI Dictionary)

A stem cell transplant may be autologous (a patient’s own blood cells saved earlier), allogeneic (blood cells donated by someone else), or syngeneic (blood cells donated by an identical twin).

(Peripheral blood stem cell transplant, NCI Dictionary)

A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with lysates from an allogeneic glioblastoma (GBM) stem-like cell line, with potential immunostimulatory and antineoplastic activities.

(Allogeneic Glioblastoma Stem-like Cell Line Lysate-pulsed Autologous Dendritic Cell Vaccine, NCI Thesaurus)