ALLELIC

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does allelic mean? 

• ALLELIC (adjective)
  The adjective ALLELIC has 1 sense:

1. of or relating to alleles

  Familiarity information: ALLELIC used as an adjective is very rare.

 Dictionary entry details 

• ALLELIC (adjective)

Sense 1

Meaning:

Of or relating to alleles

Classified under:

Relational adjectives (pertainyms)

Synonyms:

allelic; allelomorphic

Pertainym:

allele ((genetics) either of a pair (or series) of alternative forms of a gene that can occupy the same locus on a particular chromosome and that control the same character)

Derivation:

allele ((genetics) either of a pair (or series) of alternative forms of a gene that can occupy the same locus on a particular chromosome and that control the same character)

 Context examples 

Certain allelic variants of the CYP2A6 gene contribute to the poor metabolizer phenotype.

(CYP2A6 wt Allele, NCI Thesaurus)

Several allelic variants of the CYP2C19 gene contribute to the poor metabolizer phenotype.

(CYP2C19 wt Allele, NCI Thesaurus)

An allelic variant of the MME gene is associated with fetomaternal alloimmunisation with antenatal glomerulopathies and membranous glomerulonephritis (FMAIG) as well as with renal failure in early adulthood.

(MME wt Allele, NCI Thesaurus)

Allelic variants of the MTHFR gene are associated with susceptibility to numerous disorders including acute leukemia, colon cancer, neural tube defects and occlusive vascular disease.

(MTHFR wt Allele, NCI Thesaurus)

Many allelic variants of the CYP27B1 gene encode proteins that are either inactive or exhibit reduced catalytic activity which, in turn, results in vitamin D-dependent rickets type I.

(CYP27B1 wt Allele, NCI Thesaurus)

Certain allelic variants of the CYP1A2 gene contribute to the poor metabolizer phenotype, which is characterized by the inability to use cytochrome P450-dependent metabolic pathways for drug elimination.

(CYP1A2 wt Allele, NCI Thesaurus)

A heritable single nucleotide polymorphism located at the acceptor splice site in certain allelic variants of eukaryotic genes.

(Acceptor Splice Site SNP, NCI Thesaurus)

Certain allelic variants of the CYP11A1 gene result in 17-alpha-hydroxylase/17,20-lyase deficiency.

(CYP11A1 wt Allele, NCI Thesaurus)

Certain allelic variants of the CYP19A1 gene exhibit functional mutations that result in enhanced aromatase activity which, in turn, causes familial gynecomastia.

(CYP19A1 wt Allele, NCI Thesaurus)

The appearance of this condition has been limited to the loss of allelic heterozygosity at the 11q13 locus on the long arm of chromosome 11.

(Multiple Endocrine Neoplasia Type 1, NLM, Medical Subject Headings)