ALKYLATING AGENT

Pronunciation (US):

(GB):

 Dictionary entry overview: What does alkylating agent mean? 

• ALKYLATING AGENT (noun)
  The noun ALKYLATING AGENT has 1 sense:

1. an antineoplastic drug used to treat some forms of cancer

  Familiarity information: ALKYLATING AGENT used as a noun is very rare.

 Dictionary entry details 

• ALKYLATING AGENT (noun)

Sense 1

Meaning:

An antineoplastic drug used to treat some forms of cancer

Classified under:

Nouns denoting man-made objects

Hypernyms ("alkylating agent" is a kind of...):

antineoplastic; antineoplastic drug; cancer drug (any of several drugs that control or kill neoplastic cells; used in chemotherapy to kill cancer cells; all have unpleasant side effects that may include nausea and vomiting and hair loss and suppression of bone marrow function)

Hyponyms (each of the following is a kind of "alkylating agent"):

chlorambucil; Leukeran (an alkylating agent (trade name Leukeran) used to treat some kinds of cancer)

 Context examples 

A melphalan prodrug in which the alkylating agent melphalan is bound to flufenamide, with potential antineoplastic and anti-angiogenic activities.

(Melphalan-Flufenamide Prodrug, NCI Thesaurus)

This agent may potentiate the anti-tumor activity of alkylating agents.

(Methoxyamine, NCI Thesaurus)

This substance is an alkylating agent and acts as a mutagen by altering and damaging DNA and is reasonably anticipated to be a human carcinogen.

(Methyl Methanesulfonate, NCI Thesaurus)

Methylnitrosourea is an alkylating agent that is primarily used for research purposes to induce tumors and has also been studied as a chemotherapy agent for cancer treatment.

(Methylnitrosourea, NCI Thesaurus)

A bifunctional alkylating agent and phenylalanine derivative of nitrogen mustard.

(Melphalan Hydrochloride, NCI Thesaurus)

Alkylating agents exert cytotoxic and, in some cases, chemotherapeutic effects by transferring alkyl groups to DNA, thereby damaging DNA and interfering with DNA synthesis and cell division.

(Clomesone, NCI Thesaurus)

An aziridinylbenzoquinone-based alkylating agent with potential antineoplastic activity.

(Carboquone, NCI Thesaurus)

An alkylating agent structurally similar to MITOMYCIN and found to be effective in the treatment of leukemia and various other neoplasms in mice.

(Carboquone, NLM, Medical Subject Headings)

Chloromethyl methyl ether is used in the synthesis of chloromethylated compounds, as an alkylating agent, and as a solvent in the manufacture of water repellents, ion-exchange resins, and industrial polymers.

(Chloromethyl Methyl Ether, NCI Thesaurus)

Cisplatin is a type of alkylating agent.

(Cisplatin, NCI Dictionary)