ACE INHIBITOR

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does ACE inhibitor mean? 

• ACE INHIBITOR (noun)
  The noun ACE INHIBITOR has 1 sense:

1. an antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure

  Familiarity information: ACE INHIBITOR used as a noun is very rare.

 Dictionary entry details 

• ACE INHIBITOR (noun)

Sense 1

Meaning:

An antihypertensive drug that blocks the formation of angiotensin II in the kidney, leading to relaxation of the arteries; promotes the excretion of salt and water by inhibiting the activity of the angiotensin converting enzyme; also used to treat congestive heart failure

Classified under:

Nouns denoting man-made objects

Synonyms:

ACE inhibitor; angiotensin-converting enzyme inhibitor

Hypernyms ("ACE inhibitor" is a kind of...):

antihypertensive; antihypertensive drug (a drug that reduces high blood pressure)

Hyponyms (each of the following is a kind of "ACE inhibitor"):

Capoten; captopril (a drug (trade name Capoten) that blocks the formation of angiotensin in the kidneys resulting in vasodilation; used in the treatment of hypertension and congestive heart failure)

enalapril; Vasotec (an ACE inhibitor (trade name Vasotec) that blocks the formation of angiotensin in the kidney and so results in vasodilation; administered after heart attacks)

lisinopril; Prinival; Zestril (an ACE inhibiting drug (trade names Prinival or Zestril) administered as an antihypertensive and after heart attacks)

Altace; ramipril (an ACE inhibitor (trade name Altace) used to treat high blood pressure or in some patients who have had a heart attack)

Mavik; trandolapril (an ACE inhibiting drug (trade name Mavik) used in some patients after a heart attack or to treat hypertension)

 Context examples 

An ACE inhibitor is a type of antihypertensive agent.

(ACE inhibitor, NCI Dictionary)

It belongs to the family of drugs called ACE inhibitors.

(Captopril, NCI Dictionary)

Aspirin is a cyclooxygenase inhibitor with antiplatelet, analgesic, antipyretic and anti-inflammatory activities; simvastatin is a statin with a cholesterol lowering effect; and the beta-blocker atenolol as well as the ACE inhibitor ramipril and the thiazide diuretic all have blood pressure lowering activity.

(Aspirin/Simvastatin/Atenolol/Ramipril/Thiazide Capsule, NCI Thesaurus)

Although this class of agents is also used in diabetic nephropathy (kidney damage due to diabetes) and congestive heart failure, it is primarily used for the treatment of hypertension in cases where the patient is intolerant of ACE inhibitor therapy.

(Angiotensin II Receptor Antagonist, NCI Thesaurus)

These could include avoiding non-steroidal anti-inflammatory drugs such as aspirin and ibuprofen and other medications that can damage the kidneys, consuming a low-sodium and/or low-protein diet, and taking medications to protect the kidneys and lower blood pressure like ACE inhibitors or angiotensin receptor blockers.

(Acute kidney injury, chronic kidney disease each a risk of the other, NIH)

Also called ACE inhibitor.

(Angiotensin-converting enzyme inhibitor, NCI Dictionary)