ABC

Pronunciation (US):

(GB):

 Dictionary entry overview: What does ABC mean? 

• ABC (noun)
  The noun ABC has 1 sense:

1. the elementary stages of any subject (usually plural)

  Familiarity information: ABC used as a noun is very rare.

 Dictionary entry details 

• ABC (noun)

Sense 1

Meaning:

The elementary stages of any subject (usually plural)

Classified under:

Nouns denoting cognitive processes and contents

Synonyms:

ABC; ABC's; ABCs; alphabet; first principles; rudiments

Context example:

he mastered only the rudiments of geometry

Hypernyms ("ABC" is a kind of...):

basic principle; basics; bedrock; fundamental principle; fundamentals (principles from which other truths can be derived)

Domain usage:

plural; plural form (the form of a word that is used to denote more than one)

 Context examples 

P-gp, encoded by the MDR-1 gene, is a member of the ATP-binding cassette (ABC) superfamily of transmembrane transporters and is overexpressed by some MDR tumors, preventing the intracellular accumulation of various cytotoxic agents.

(Irinotecan/P-glycoprotein Inhibitor HM30181AK Combination Tablet, NCI Thesaurus)

P-gp, encoded by the MDR-1 gene and a member of the ATP-binding cassette (ABC) superfamily of transmembrane transporters, is overexpressed by some MDR tumors and may contribute to multidrug resistance to chemotherapy.

(Carbon C 11 N-desmethyl-Loperamide, NCI Thesaurus)

This transporter protein is similar to ABC superfamily of transport systems and is over expressed in a multidrug-resistant SCLC cell line.

(ATP-Binding Cassette, Sub-Family C, Member 1, NCI Thesaurus)

ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).

(ATP-Binding Cassette, Sub-Family B, Member 6, NCI Thesaurus)

Upon binding to various ligands, three classes of proteins are synthesized including lipid binding proteins, the ATP-binding cassette (ABC) transporters and cytochrome P450 member proteins which catalyze lipid anabolism, metabolism, and elimination.

(Lipid Metabolism and Toxicity Pathway, NCI Thesaurus/BIOCARTA)

P-gp is a transmembrane ATP-binding cassette (ABC) transporter and is overexpressed by some multidrug resistant tumors.

(MDR modulator CBT-1, NCI Thesaurus)

An inhibitor of the adenosine triphosphate (ATP)-binding cassette (ABC) transporter P-glycoprotein (P-gp), with adjuvant activity.

(P-glycoprotein Inhibitor HM30181AK, NCI Thesaurus)

P-gp, encoded by the MDR-1 gene, is a member of the ATP-binding cassette (ABC) superfamily of transmembrane transporters; it prevents the intestinal uptake and intracellular accumulation of various cytotoxic agents.

(Oraxol, NCI Thesaurus)

There are seven major families of ABC(ATP-binding cassette) proteins, two of them are shown on this pathway, MDR/TAP (Multi-Drug Resistance) and MRP (Multi-Drug Resistance Related Proteins).

(Multi-Drug Resistance Factor Pathway, NCI Thesaurus/BIOCARTA)

The ATP-binding cassette (ABC) transporters form one of the largest known protein families and are widespread in bacteria, archaea, and eukaryotes.

(ABC Transporter Pathway, NCI Thesaurus/KEGG)