5-HYDROXYTRYPTAMINE

 Dictionary entry overview: What does 5-hydroxytryptamine mean? 

• 5-HYDROXYTRYPTAMINE (noun)
  The noun 5-HYDROXYTRYPTAMINE has 1 sense:

1. a neurotransmitter involved in e.g. sleep and depression and memory

  Familiarity information: 5-HYDROXYTRYPTAMINE used as a noun is very rare.

 Dictionary entry details 

• 5-HYDROXYTRYPTAMINE (noun)

Sense 1

Meaning:

A neurotransmitter involved in e.g. sleep and depression and memory

Classified under:

Nouns denoting substances

Synonyms:

5-hydroxytryptamine; serotonin

Hypernyms ("5-hydroxytryptamine" is a kind of...):

monoamine neurotransmitter (a monoamine that is functionally important in neural transmission)

 Context examples 

In vivo, oxitriptan (or 5-hydroxytryptophan) is converted into 5-hydroxytryptamine (5-HT or serotonin) as well as other neurotransmitters.

(Oxitriptan, NCI Thesaurus)

Palonosetron competitively blocks the action of serotonin at 5-hydroxytryptamine type 3 (5-HT3) receptors located on vagal afferents in the chemoreceptor trigger zone (CTZ), resulting in suppression of chemotherapy-induced nausea and vomiting.

(Palonosetron hydrochloride, NCI Thesaurus)

This agent also may block 5-hydroxytryptamine (5-HT) receptors and stimulate release of histamine from mast cells.

(Phentolamine, NCI Thesaurus)

This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors.

(Mirtazapine, NCI Thesaurus)

Memantine is also a 5-hydroxytryptamine type 3 (5HT3) receptor and nicotinic receptor antagonist.

(Memantine hydrochloride, NCI Thesaurus)

This allele, which encodes 5-hydroxytryptamine receptor 1A protein, plays a role in both neurotransmitter binding and G protein-coupled receptor signaling.

(HTR1A wt Allele, NCI Thesaurus)

This allele, which encodes 5-hydroxytryptamine 3 receptor protein, plays a role in the regulation of a biogenic hormone that has diverse functionalities.

(HTR3A wt Allele, NCI Thesaurus)

This allele, which encodes 5-hydroxytryptamine 2A receptor protein, is involved in several processes that activate a PI-calcium second messenger system via G-protein association, such as tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.

(HTR2A wt Allele, NCI Thesaurus)