TETHERED

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 Dictionary entry overview: What does tethered mean? 

• TETHERED (adjective)
  The adjective TETHERED has 1 sense:

1. confined or restricted with or as if with a rope or chain

  Familiarity information: TETHERED used as an adjective is very rare.

 Dictionary entry details 

• TETHERED (adjective)

Sense 1

Meaning:

Confined or restricted with or as if with a rope or chain

Similar:

bound (confined by bonds)

 Context examples 

By the door a horse stood tethered, the ruddy glow beating strongly upon his brown head and patient eyes, while his body stood back in the shadow.

(The White Company, by Sir Arthur Conan Doyle)

A polymeric prodrug consisting of the fumagillol-derived small molecule XMT-1191 tethered to the hydrophilic, biodegradable70 kDa polymer poly[1-hydroxymethylethylene hydroxymethylformal] (PHF) with potential antiangiogenic and antineoplastic activities.

(Fumagillin-Derived Polymer Conjugate XMT-1107, NCI Thesaurus)

I light a fire, for we have brought supply of wood with us, and she prepare food while I undo the horses and set them, tethered in shelter, to feed.

(Dracula, by Bram Stoker)

The protease-activated receptors PAR1 and PAR4 are cleaved by the protease thrombin, releasing a tethered peptide ligand that activates the receptor and triggers intracellular calcium release.

(Aspirin Inhibition of Platelet Activation Pathway, NCI Thesaurus/BIOCARTA)

A preparation of glucocorticoid receptor (GR) negative, allogeneic cytotoxic T-lymphocytes (CTLs) expressing a membrane-tethered interleukin 13 (IL13) cytokine chimeric T-cell antigen receptor (zetakine), with potential antineoplastic activity.

(Allogeneic IL13-Zetakine/HyTK-Expressing-Glucocorticoid Resistant Cytotoxic T Lymphocytes GRm13Z40-2, NCI Thesaurus)

Have you not tethered a young kid under a tree, lain above it with your rifle, and waited for the bait to bring up your tiger?

(The Return of Sherlock Holmes, by Sir Arthur Conan Doyle)

About the centre, and a good way behind the rest, Silver and I followed—I tethered by my rope, he ploughing, with deep pants, among the sliding gravel.

(Treasure Island, by Robert Louis Stevenson)

The PRC2 complex is probably tethered to promoters of affected genes through the interaction with specific DNA binding factors, such as YY1, a zinc finger transcription factor that acts as both a positive and negative regulator of transcription of cellular and viral genes.

(Gene Silencing Pathway, NCI Thesaurus/BIOCARTA)

Slowly the long and glittering train wound into the lists, until every horse had been tethered by the varlets in waiting, and every lord and lady seated in the long stands which stretched, rich in tapestry and velvet and blazoned arms, on either side of the centre of the arena.

(The White Company, by Sir Arthur Conan Doyle)

A dry-wood fire had been lit, and round this the leaders crouched, the glare beating upon their rugged faces, while the hardy archers lounged and chatted amid the tethered horses, while they munched their scanty provisions.

(The White Company, by Sir Arthur Conan Doyle)